Ube2t Protein (His tag)

Catalog No. ABIN7198597

This Recombinant Ube2t protein is expressed in Escherichia coli (E. coli).

Quick Overview for Ube2t Protein (His tag) (ABIN7198597)

Target: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 90 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This Ube2t protein is labelled with His tag.

Purpose: Recombinant Human UBE2T Protein (His Tag)

Sequence: Met 1-Val197

Characteristics: A DNA sequence encoding the human UBE2T (Q9NPD8) (Met1-Val197) was fused with a polyhistidine tag at the C-terminus.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, 30 % glycerol, 0.1 % Tween 20, 0.4 mM Chaps, pH 7.5

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Alternative Name: UBE2T

Background:

Background: Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers, representing an attractive target for the development of inhibitors. Notably, UBE2T locates at 1q32.1, and the gain of 1q is frequently observed in a variety of cancers. For instance, UBE2T serves an important role in the growth of bladder cancer cells, and may be considered as a potential biomarker and therapeutic target for bladder cancer.

Synonym: Ubiquitin-Conjugating Enzyme E2 T, Cell Proliferation-Inducing Gene 50 Protein, Ubiquitin Carrier Protein T, Ubiquitin-Protein Ligase T, UBE2T

Molecular Weight: 23.9 kDa

UniProt: Q9NPD8

Pathways: Chromatin Binding