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ULBP2 Protein (Fc Tag)

ULBP2 Origin: Human Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7318835
  • Target See all ULBP2 Proteins
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    Human
    Source
    • 7
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This ULBP2 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human ULBP2/N2DL-2 Protein (Fc Tag)(Active)
    Sequence
    Gly26-Ser217
    Characteristics
    Recombinant Human UL16 Binding Protein-2/NKG2D ligand 2 is produced by our Mammalian expression system and the target gene encoding Gly26-Ser217 is expressed with a Fc tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human NKG2DL2-Fc at 8μg/ml(100 μl/well) can bind Human NKG2D-His(Cat: PKSH033409). The ED50 of Human NKG2DL2-Fc is 10.32 ug/ml .
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    Discover our top product ULBP2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    Alternative Name
    ULBP2/N2DL-2 (ULBP2 Products)
    Synonyms
    N2DL2 Protein, RAET1H Protein, UL16 binding protein 2 Protein, NKG2D ligand 2-like Protein, ULBP2 Protein, LOC100355436 Protein
    Background

    Background: NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance.

    Synonym: NKG2D Ligand 2, N2DL-2, NKG2DL2, ALCAN-Alpha, Retinoic Acid Early Transcript 1H, UL16-Binding Protein 2, ULBP2, N2DL2, RAET1H

    Molecular Weight
    51.4 kDa
    UniProt
    Q9BZM5
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