ULBP2 Protein (Fc Tag,His tag)
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- Target See all ULBP2 Proteins
- ULBP2 (UL16 Binding Protein 2 (ULBP2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ULBP2 protein is labelled with Fc Tag,His tag.
- Purpose
- Active Recombinant Human NKG2D ligand 2/ULBP2 Protein
- Sequence
- GRADPHSLCY DITVIPKFRP GPRWCAVQGQ VDEKTFLHYD CGNKTVTPVS PLGKKLNVTT AWKAQNPVLR EVVDILTEQL RDIQLENYTP KEPLTLQARM SCEQKAEGHS SGSWQFSFDG QIFLLFDSEK RMWTTVHPGA RKMKEKWEND KVVAMSFHYF SMGDCIGWLE DFLMGMDSTL EPSAGAPLAM SS
- Specificity
- Gly26-Ser217
- Purity
- > 92 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Human ULBP2 Protein at 2μg/mL (100 μL/well) can bind NKG2D-raFc with a linear range of 1.95-336.7ng/mL.
- Top Product
- Discover our top product ULBP2 Protein
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UL16 Binding Protein 2 (ULBP2) (AA 26-217) protein (His-Avi Tag)
ULBP2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
UL16 Binding Protein 2 (ULBP2) protein (His-Avi Tag,Biotin)ULBP2 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
UL16 Binding Protein 2 (ULBP2) (AA 25-224) protein (His tag)ULBP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
UL16 Binding Protein 2 (ULBP2) (AA 1-246) protein (GST tag)ULBP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
UL16 Binding Protein 2 (ULBP2) (AA 26-216) protein (His tag)Crystallography grade ULBP2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- ULBP2 (UL16 Binding Protein 2 (ULBP2))
- Alternative Name
- NKG2D ligand 2/ULBP2 (ULBP2 Products)
- Synonyms
- N2DL2 Protein, RAET1H Protein, UL16 binding protein 2 Protein, NKG2D ligand 2-like Protein, ULBP2 Protein, LOC100355436 Protein
- Background
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Description: ULBP2 Protein, Human, Recombinant (His Tag) consists of 203 amino acids with a molecular weight of 23.2 kDa. The apparent molecular mass of recombinant human ULBP2 is about 33 kDa in SDS-PAGE under reducing conditions because of glycosylation.NKG2D ligand 2 is cell membrane protein belonging to theMHC class I family.The gene for ULBP-2 resides in a cluster of ten related genes, six of which encode potentially functional glycoproteins. ULBPs are known to bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, gamma δ T cells, and CD8+ alpha beta T cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway.ULBP2 / N2DL-2 is not expressed in normal tissues, but in various types of cancer cell lines and the fetus and has been implicated in tumor surveillance.
Name: ULBP2,ALCAN-alpha,N2DL2,NKG2DL2,RAET1H
- Gene ID
- 80328
- UniProt
- Q9BZM5
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