UROS Protein (His tag)
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- Target See all UROS Proteins
- UROS (Uroporphyrinogen III Synthase (UROS))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UROS protein is labelled with His tag.
- Purpose
- Recombinant Human UROS/UROIIIS Protein (His Tag)
- Sequence
- Met 1-Cys265
- Characteristics
- Recombinant Human Uroporphyrinogen-III Synthase is produced by our E.coli expression system and the target gene encoding Met1-Cys265 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product UROS Protein
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Uroporphyrinogen III Synthase (UROS) (AA 1-265) protein (His tag)
custom-made UROS Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Uroporphyrinogen III Synthase (UROS) (AA 1-265) protein (His tag)custom-made UROS Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Uroporphyrinogen III Synthase (UROS) (AA 1-265) protein (His tag)UROS Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Uroporphyrinogen III Synthase (UROS) (AA 1-265) protein (GST tag)UROS Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Uroporphyrinogen III Synthase (UROS) protein (Myc-DYKDDDDK Tag)UROS Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 10 % Glycerol, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- UROS (Uroporphyrinogen III Synthase (UROS))
- Alternative Name
- UROS/UROIIIS (UROS Products)
- Background
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Background: Uroporphyrinogen-III Synthase is an enzyme which belongs to the uroporphyrinogen-III synthase family. Uroporphyrinogen-III Synthase is ubiquitous and it is involved in Porphyrin metabolism. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as Methionine synthesis (Vitamin B12) or oxygen transport (Heme). Uroporphyrinogen-III Synthase can catalyze cyclization of the linear Tetrapyrrole, Hydroxymethylbilane, to the Macrocyclic Uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of Porphyrins. Defects in Uroporphyrinogen-III Synthase are the cause of Congenital Erythropoietic Porphyria (CEP).
Synonym: Uroporphyrinogen-III Synthase, UROIIIS, UROS, Hydroxymethylbilane Hydrolyase [Cyclizing], Uroporphyrinogen-III Cosynthase, UROS
- Molecular Weight
- 29.7 kDa
- UniProt
- P10746
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