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Apolipoprotein C-II Protein (APOC2) (His tag)

Recombinant Apolipoprotein C-II protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318171

Quick Overview for Apolipoprotein C-II Protein (APOC2) (His tag) (ABIN7318171)

Target

See all Apolipoprotein C-II (APOC2) Proteins
Apolipoprotein C-II (APOC2)

Protein Type

Recombinant

Origin

  • 8
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 10
  • 6
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This Apolipoprotein C-II protein is labelled with His tag.

    Purpose

    Recombinant Human Apolipoprotein C-II/APOC2 Protein (His Tag)

    Sequence

    Met 1-Glu82

    Characteristics

    Recombinant Human Apolipoprotein C-II is produced by our E.coli expression system and the target gene encoding Met1-Glu82 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Comment

    14 kDa

    Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mMPB,150 mM NaCL,30 % glycerol, pH 7.2.

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    Apolipoprotein C-II (APOC2)

    Alternative Name

    Apolipoprotein C-II

    Background

    Background: APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.

    Synonym: Apolipoprotein C-II, Apolipoprotein C2, APC2 and APOC2

    Molecular Weight

    10.0 kDa

    UniProt

    P02655

    Pathways

    Lipid Metabolism
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