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Calcineurin B Protein (CAN) (His tag)

This Recombinant Calcineurin B protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318221

Quick Overview for Calcineurin B Protein (CAN) (His tag) (ABIN7318221)

Target

See all Calcineurin B (CAN) Proteins
Calcineurin B (CAN)

Protein Type

Recombinant

Origin

  • 4
  • 1
  • 1
Human

Source

  • 2
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This Calcineurin B protein is labelled with His tag.

    Purpose

    Recombinant Human Calcineurin B/CNB Protein (His Tag)

    Sequence

    Met 1-Val170

    Characteristics

    Recombinant Human Calcineurin Subunit B Type 1 is produced by our E.coli expression system and the target gene encoding Met1-Val170 is expressed with a 6His tag at the N-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Comment

    18 kDa

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 2 mM DTT, pH 8.0 .

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    Calcineurin B (CAN)

    Alternative Name

    Calcineurin B

    Background

    Background: Calcineurin Subunit B Type 1 belongs to the calcineurin regulatory subunit family. Calcineurin Subunit B Type 1 is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase. It is composed of a catalytic subunit (A) and a regulatory subunit (B). It contains four EF-hand domains and four functional calcium-binding sites. Calcineurin Subunit B Type 1 plays an improtant role in the T cell activation pathway.

    Synonym: Calcineurin Subunit B Type 1, Protein Phosphatase 2B Regulatory Subunit 1, Protein Phosphatase 3 Regulatory Subunit B Alpha Osoform 1, PPP3R1, CNA2, CNB

    Molecular Weight

    21.5 kDa

    UniProt

    P63098

    Pathways

    Cellular Glucan Metabolic Process, VEGF Signaling
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