Annexin a1 Protein (AA 1-346) (His tag)

Catalog No. ABIN7273847

Recombinant Annexin a1 protein expressed in Escherichia coli (E. coli).

Quick Overview for Annexin a1 Protein (AA 1-346) (His tag) (ABIN7273847)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Protein Type: Recombinant

Origin: Mouse

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Product Details

Protein Characteristics: AA 1-346

Purification tag / Conjugate: This Annexin a1 protein is labelled with His tag.

Purpose: Mouse ANXA1 Protein

Sequence: Met1-Asn346

Characteristics: Recombinant Mouse ANXA1 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Met1-Asn346.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in 20 mM Tris, 150 mM NaCl ( pH 8.2). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: ANXA1

Background: Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance.

Molecular Weight: 39.6 kDa same as Tris-Bis PAGE result.

UniProt: P10107

Pathways: Hormone Transport