APOA1 Protein (AA 25-267) (Fc Tag)
Quick Overview for APOA1 Protein (AA 25-267) (Fc Tag) (ABIN7273867)
Target
See all APOA1 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 25-267
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Purification tag / Conjugate
- This APOA1 protein is labelled with Fc Tag.
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Purpose
- Human APOA1 Protein
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Sequence
- Asp25-Gln267
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Characteristics
- Recombinant Human APOA1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asp25-Gln267.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- APOA1 (Apolipoprotein A-I (APOA1))
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Alternative Name
- APOA1
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Background
- Apolipoprotein A1 (ApoA1) is a main protein moiety in high-density lipoprotein (HDL) particles. Generally, ApoA1 and HDL are considered as atheroprotective. In prooxidant and inflammatory microenvironment in the vicinity to the atherosclerotic lesion, ApoA1/HDL are subjected to modification. The chemical modifications such as oxidation, nitration, etc result in altering native architecture of ApoA1 toward dysfunctionality and abnormality.
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Molecular Weight
- 54.8 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
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UniProt
- P02647
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Pathways
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
Target
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