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APOA1 Protein (AA 25-264) (Fc Tag)

This Recombinant APOA1 protein is expressed in HEK-293 Cells.
Catalog No. ABIN7273870

Quick Overview for APOA1 Protein (AA 25-264) (Fc Tag) (ABIN7273870)

Target

See all APOA1 Proteins
APOA1 (Apolipoprotein A-I (APOA1))

Protein Type

Recombinant

Origin

  • 19
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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Mouse

Source

  • 25
  • 17
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 25-264

    Purification tag / Conjugate

    This APOA1 protein is labelled with Fc Tag.

    Purpose

    Mouse APOA1 Protein

    Sequence

    Asp25-Gln264

    Characteristics

    Recombinant Mouse APOA1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asp25-Gln264.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    APOA1 (Apolipoprotein A-I (APOA1))

    Alternative Name

    APOA1

    Background

    Apolipoprotein A1 (ApoA1) is a main protein moiety in high-density lipoprotein (HDL) particles. Generally, ApoA1 and HDL are considered as atheroprotective. In prooxidant and inflammatory microenvironment in the vicinity to the atherosclerotic lesion, ApoA1/HDL are subjected to modification. The chemical modifications such as oxidation, nitration, etc result in altering native architecture of ApoA1 toward dysfunctionality and abnormality.

    Molecular Weight

    54.7 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

    UniProt

    Q00623

    Pathways

    Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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