TNFRSF13C Protein (AA 7-71) (His tag)
Quick Overview for TNFRSF13C Protein (AA 7-71) (His tag) (ABIN7273907)
Target
See all TNFRSF13C ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 7-71
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Purification tag / Conjugate
- This TNFRSF13C protein is labelled with His tag.
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Purpose
- Cynomolgus BAFFR/TNFRSF13C Protein
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Sequence
- Ser7-Ala71
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Characteristics
- Recombinant Cynomolgus BAFFR/TNFRSF13C Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser7-Ala71.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Cynomolgus BAFFR, His Tag at 1μg/ml (100μl/Well) on plate.Dose response curve for Anti-BAFFR Ab., hFc Tag with the EC50 of 11.1ng/ml determined by ELISA. See testing image for detail.
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Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (His tag)
TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (His-Avi Tag,Biotin)TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (Fc Tag)TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (mFc Tag)TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 1-175) protein (His tag)custom-made TNFRSF13C Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 1-184) protein (His tag)custom-made TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (Active) proteinTNFRSF13C Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 10-71) protein (Fc Tag)TNFRSF13C Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 10-71) (Active) protein (Fc Tag)TNFRSF13C Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-76) (Active) protein (His tag)TNFRSF13C Origin: Cynomolgus Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
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Alternative Name
- BAFFR
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Background
- BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.
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Molecular Weight
- 7.7 kDa. Due to glycosylation, the protein migrates to 13-25 kDa based on Tris-Bis PAGE result.
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NCBI Accession
- XP_001101623
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Pathways
- NF-kappaB Signaling
Target
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