CD180 Protein (AA 21-626) (His tag)
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- Target See all CD180 Proteins
- CD180 (CD180 Molecule (CD180))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-626
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD180 protein is labelled with His tag.
- Purpose
- Mouse CD180 Protein
- Sequence
- Thr21-Ser626
- Characteristics
- Recombinant Mouse CD180 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr21-Ser626.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD180 (CD180 Molecule (CD180))
- Alternative Name
- CD180 (CD180 Products)
- Background
- CD180, a related member of the Toll-like receptor family, is lost or underexpressed at the plasma membrane in circulating cells of various B-cell lymphomas except marginal zone lymphomas (MZL).CD180 can be considered as a single positive robust marker of MZL and should be therefore included in flow cytometry panels for the diagnosis of mature B-cell neoplasms.
- Molecular Weight
- 69.1 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
- UniProt
- Q62192
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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