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CD180 Products

(CD180 Molecule (CD180))
CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq, Jul 2008].

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Featured CD180 Categories

CD180 Antibodies

High quality antibodies with extensive validation data.

CD180 ELISA Kits

Reliable ELISA kits for a wide range of species.

CD180 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD180 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, IP, Func
Validations
  • (3)
  • (2)
Cat. No. ABIN2749219
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application FACS, IP
Validations
  • (3)
  • (2)
Cat. No. ABIN559680
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3181467
Quantity 100 μL
Datasheet Datasheet

Recommended CD180 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730645
Quantity 96 tests
Datasheet Datasheet

Recommended CD180 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274092
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320258
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320259
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD180 products

Egli, Zajonz, Burger, Schweighoffer: "Human CD180 Transmits Signals via the PIM-1L Kinase." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142741, (2015) (PubMed).

Geraldes, Rebrovich, Herrmann, Wong, Jäck, Wabl, Cascalho: "Ig heavy chain promotes mature B cell survival in the absence of light chain." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 3, pp. 1659-68, (2007) (PubMed).

Nagai, Kobayashi, Motoi, Ishiguro, Akashi, Saitoh, Kusumoto, Kaisho, Akira, Matsumoto, Takatsu, Miyake: "The radioprotective 105/MD-1 complex links TLR2 and TLR4/MD-2 in antibody response to microbial membranes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7043-9, (2005) (PubMed).

Divanovic, Trompette, Atabani, Madan, Golenbock, Visintin, Finberg, Tarakhovsky, Vogel, Belkaid, Kurt-Jones, Karp: "Inhibition of TLR-4/MD-2 signaling by RP105/MD-1." in: Journal of endotoxin research, Vol. 11, Issue 6, pp. 363-8, (2005) (PubMed).

Tsuneyoshi, Fukudome, Kohara, Tomimasu, Gauchat, Nakatake, Kimoto: "The functional and structural properties of MD-2 required for lipopolysaccharide binding are absent in MD-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 1, pp. 340-4, (2004) (PubMed).

Olson, Graves, Shu, Ryan, Clark: "Caspase activity is required for stimulated B lymphocytes to enter the cell cycle." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 12, pp. 6065-72, (2003) (PubMed).

Janeway, Medzhitov: "Innate immune recognition." in: Annual review of immunology, Vol. 20, pp. 197-216, (2002) (PubMed).

Nagai, Shimazu, Ogata, Akashi, Sudo, Yamasaki, Hayashi, Iwakura, Kimoto, Miyake: "Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide." in: Blood, Vol. 99, Issue 5, pp. 1699-705, (2002) (PubMed).

Ogata, Su, Miyake, Nagai, Akashi, Mecklenbräuker, Rajewsky, Kimoto, Tarakhovsky: "The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells." in: The Journal of experimental medicine, Vol. 192, Issue 1, pp. 23-9, (2000) (PubMed).

Synonyms and alternative names related to CD180

CD180 molecule (Cd180), CD180 molecule (CD180), CD180 antigen (Cd180), CD180, F630107B15, LY64, Ly78, RP105

Protein level used designations for CD180

  • CD180 antigen
  • lymphocyte antigen 78
  • CD180 molecule
  • radio protective 105
  • lymphocyte antigen 64-like protein
  • ly-78
  • radioprotective 105 kDa protein
  • lymphocyte antigen 64
  • lymphocyte antigen-64, radioprotective, 105kDa
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