P-Cadherin Protein (CDH3) (AA 108-654) (His tag)
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- Target See all P-Cadherin (CDH3) Proteins
- P-Cadherin (CDH3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 108-654
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This P-Cadherin protein is labelled with His tag.
- Purpose
- Human CDH3/Cadherin 3 Protein
- Sequence
- Asp108-Gly654
- Characteristics
- Recombinant Human CDH3/Cadherin 3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp108-Gly654.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- P-Cadherin (CDH3)
- Alternative Name
- CDH3 (CDH3 Products)
- Background
- Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been proved it could be a serum marker to monitor colorectal cancer. Inhibited CDH3 expression could upregulate E-cadherin, downregulated N-cadherin, which may control invasion and migration.
- Molecular Weight
- 64.32 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
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