OB Cadherin Protein (AA 54-617) (His tag)
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- Target See all OB Cadherin (CDH11) Proteins
- OB Cadherin (CDH11) (Cadherin 11 (CDH11))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 54-617
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This OB Cadherin protein is labelled with His tag.
- Purpose
- Human CDH11/Cadherin 11 Protein
- Sequence
- Gly54-Thr617
- Characteristics
- Recombinant Human CDH11/Cadherin 11 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly54-Thr617.
- Purity
- > 90 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- OB Cadherin (CDH11) (Cadherin 11 (CDH11))
- Alternative Name
- CDH11 (CDH11 Products)
- Background
- CDH11 belongs to a group of transmembrane proteins that are principally located in adherens junctions. CDH11 mediates homophilic cell-to-cell adhesion, which may promote the development of cirrhosis. CDH11 expression was positively correlated with liver fibrosis in patients with cirrhosis, and could therefore be a prognostic factor in patients with liver fibrosis.
- Molecular Weight
- 66.32 kDa. Due to glycosylation, the protein migrates to 67-70 kDa based on Tris-Bis PAGE result.
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