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CTGF Protein (AA 27-349) (Fc Tag)

This Recombinant CTGF protein is expressed in HEK-293 Cells.
Catalog No. ABIN7274341

Quick Overview for CTGF Protein (AA 27-349) (Fc Tag) (ABIN7274341)

Target

See all CTGF Proteins
CTGF (Connective Tissue Growth Factor (CTGF))

Protein Type

Recombinant

Origin

  • 24
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Human

Source

  • 32
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 27-349

    Purification tag / Conjugate

    This CTGF protein is labelled with Fc Tag.

    Purpose

    Human CTGF/CCN2 Protein

    Sequence

    Gln27-Ala349

    Characteristics

    Recombinant Human CTGF/CCN2 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln27-Ala349.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human CTGF, hFc Tag at 0.2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-CTGF Antibody, hFc Tag with the EC50 of 14.2ng/ml determined by ELISA. See testing image for detail.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    CTGF (Connective Tissue Growth Factor (CTGF))

    Alternative Name

    CTGF

    Background

    Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells.

    Molecular Weight

    61.77 kDa. Due to glycosylation, the protein migrates to 50-55 kDa and 62-72 kDa based on Tris-Bis PAGE result.

    UniProt

    Q5M8T4

    Pathways

    Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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