FCRL2 Protein (AA 20-401) (His tag)
Quick Overview for FCRL2 Protein (AA 20-401) (His tag) (ABIN7274591)
Target
See all FCRL2 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 20-401
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Purification tag / Conjugate
- This FCRL2 protein is labelled with His tag.
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Purpose
- Human FCRL2/IRTA4 Protein
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Sequence
- Leu20-Val401
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Characteristics
- Recombinant Human FCRL2/IRTA4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-Val401.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human FCRL2, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-FCRL2 Antibody, hFc Tag with the EC50 of 0.17μg/ml determined by ELISA. See testing image for detail.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- FCRL2 (Fc Receptor-Like 2 (FCRL2))
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Alternative Name
- FCRL2
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Background
- Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 mRNA expression was found to be expressed at considerably higher levels in peripheral blood mononuclear cells (PBMC) of B-CLL patients compared to controls (range 1.35- to 210-fold upregulation, P < 0.0001) and cells of other hematological diseases.
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Molecular Weight
- 42.7 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
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UniProt
- Q96LA5-1
Target
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