FGF10 Protein
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- Target See all FGF10 Proteins
- FGF10 (Fibroblast Growth Factor 10 (FGF10))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- Gln38-Ser208
- Purity
- > 90% as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.299 nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product FGF10 Protein
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Fibroblast Growth Factor 10 (FGF10) (AA 38-208) protein (Biotin)
FGF10 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Growth Factor 10 (FGF10) (AA 37-215) protein (His tag)FGF10 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 10 (FGF10) (AA 1-208) protein (GST tag)FGF10 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 10 (FGF10) (AA 38-137) protein (GST tag)FGF10 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in 20 mM Tris, 150 mM NaCl ( pH 8.0). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FGF10 (Fibroblast Growth Factor 10 (FGF10))
- Alternative Name
- FGF10 (FGF10 Products)
- Background
- FGF-10, KGF2,Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease.
- Molecular Weight
- 19.3 kDa. The protein migrates to 25 kDa based on Tris-Bis PAGE result.
- UniProt
- O15520
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
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