IDH1 Protein (AA 2-414) (His tag)
Quick Overview for IDH1 Protein (AA 2-414) (His tag) (ABIN7274843)
Target
See all IDH1 ProteinsProtein Type
Origin
Source
Purity
-
-
Protein Characteristics
- AA 2-414
-
Purification tag / Conjugate
- This IDH1 protein is labelled with His tag.
-
Purpose
- Human IDH1 Protein
-
Sequence
- Ser2-Leu414
-
Characteristics
- Recombinant Human IDH1 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Ser2-Leu414.
-
Sterility
- 0.22 μm filtered
-
Endotoxin Level
- Less than 1EU per μg by the LAL method.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 341-414) protein (His-IF2DI Tag)
IDH1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 1-414) protein (His tag)IDH1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 1-414) protein (GST tag)IDH1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Supplied as 0.22μm filtered solution in 50 mM Tris, 200 mM NaCl, 1 mM DTT, 10 % Glycerol ( pH 7.5).
-
Preservative
- Dithiothreitol (DTT)
-
Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -80 °C
-
Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
-
Expiry Date
- 12 months
-
-
- IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
-
Alternative Name
- IDH1
-
Background
- Isocitrate dehydrogenase (IDH) is a metabolic enzyme that converts isocitrate to α-ketoglutarate (α-KG). Genetic gain-of-function mutations in IDH1 and IDH2 confer a neomorphic activity that allow reduction of α -KG to (R)-2- hydroxyglutarate, the accumulation of which results in the development of cancers like low grade gliomas and leukemia.Isocitrate dehydrogenase 1 (IDH1) is the most frequently mutated metabolic gene in cancer.
-
Molecular Weight
- 47.35 kDa same as Tris-Bis PAGE result.
-
UniProt
- O75874
-
Pathways
- Warburg Effect
Target
-
