IL-20 Protein (AA 25-176) (His tag)

Catalog No. ABIN7274930

Recombinant IL-20 protein expressed in HEK-293 Cells.

Quick Overview for IL-20 Protein (AA 25-176) (His tag) (ABIN7274930)

Target: IL-20 (IL20) (Interleukin 20 (IL20))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Product Details

Protein Characteristics: AA 25-176

Purification tag / Conjugate: This IL-20 protein is labelled with His tag.

Purpose: Mouse IL-20 Protein

Sequence: Leu25-Leu176

Characteristics: Recombinant Mouse IL-20 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Leu25- Leu176.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Biological Activity Comment: The affinity constant of 14.26 μM as determined in SPR assay (Biacore T200). See testing image for detail.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM PB, 500 mM NaCl ( pH 8.0).

Storage: -80 °C

Storage Comment: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: IL-20 (IL20) (Interleukin 20 (IL20))

Alternative Name: IL-20

Background: Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC.

Molecular Weight: 19.5 kDa. Due to glycosylation, the protein migrates to 20-22 kDa based on Tris-Bis PAGE result.

UniProt: Q9JKV9

Pathways: Protein targeting to Nucleus