IL-33 Protein (AA 109-270) (His tag)
Quick Overview for IL-33 Protein (AA 109-270) (His tag) (ABIN7274937)
Target
See all IL-33 (IL33) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 109-270
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Purification tag / Conjugate
- This IL-33 protein is labelled with His tag.
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Purpose
- Cynomolgus IL-33 Protein
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Sequence
- His109-Ile270
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Characteristics
- Recombinant Cynomolgus IL-33 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains His109-Ile270.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- IL-33 (IL33) (Interleukin 33 (IL33))
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Alternative Name
- IL-33
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Background
- Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are expressed in epithelial barrier tissues and endothelial barriers. ST2 is a receptor for IL-33, expressed selectively on a subset of Th2 cells, mediating some of their functions.
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Molecular Weight
- 19.2 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.
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Pathways
- Production of Molecular Mediator of Immune Response
Target
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