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IL-33 Protein (AA 109-270) (His tag)

This Recombinant IL-33 protein is produced in HEK-293 Cells.
Catalog No. ABIN7274937

Quick Overview for IL-33 Protein (AA 109-270) (His tag) (ABIN7274937)

Target

See all IL-33 (IL33) Proteins
IL-33 (IL33) (Interleukin 33 (IL33))

Protein Type

Recombinant

Origin

  • 22
  • 20
  • 4
  • 1
  • 1
  • 1
  • 1
Cynomolgus

Source

  • 29
  • 11
  • 2
  • 2
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by Tris-Bis PAGE
  • Protein Characteristics

    AA 109-270

    Purification tag / Conjugate

    This IL-33 protein is labelled with His tag.

    Purpose

    Cynomolgus IL-33 Protein

    Sequence

    His109-Ile270

    Characteristics

    Recombinant Cynomolgus IL-33 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains His109-Ile270.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    IL-33 (IL33) (Interleukin 33 (IL33))

    Alternative Name

    IL-33

    Background

    Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are expressed in epithelial barrier tissues and endothelial barriers. ST2 is a receptor for IL-33, expressed selectively on a subset of Th2 cells, mediating some of their functions.

    Molecular Weight

    19.2 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.

    Pathways

    Production of Molecular Mediator of Immune Response
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