NKG2A & CD94 (AA 98-244) protein (mFc Tag)
Quick Overview for NKG2A & CD94 (AA 98-244) protein (mFc Tag) (ABIN7275332)
Target
Protein Type
Origin
Source
Purity
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Protein Characteristics
- AA 98-244
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Purification tag / Conjugate
- mFc Tag
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Purpose
- Mouse NKG2A&CD94 Protein
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Sequence
- Asn98-Ile244(NKG2A) & Ile32-Ile179(CD94)
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Specificity
- Uni-Prot: Q9WU31 (NKG2A), O54707 (CD94)
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Characteristics
- Recombinant Mouse NKG2A&CD94 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Asn98-Ile244(NKG2A)&Ile32-Ile179(CD94).
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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NKG2A & CD94 (AA 100-233) protein (mFc Tag)
Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
NKG2A & CD94 (AA 100-233) protein (His-Avi Tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
NKG2A & CD94 (AA 100-233) protein (Fc Tag,DYKDDDDK Tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
NKG2A & CD94 (AA 100-233) protein (His-Avi Tag,Biotin)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
NKG2A & CD94 (AA 100-219) protein (Fc Tag,DYKDDDDK Tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
NKG2A & CD94 (AA 94-233) protein (His tag,DYKDDDDK Tag)Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
NKG2A & CD94 (AA 113-233) protein (Fc Tag)Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
NKG2A & CD94 (AA 113-233), (AA 57-179) (Active) protein (Fc Tag,AVI tag,Biotin)Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- NKG2A & CD94
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Alternative Name
- NKG2A&CD94
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Background
- The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies.
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Molecular Weight
- 18.3 kDa (CD94) and 43.1 kDa (NKG2A). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
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UniProt
- Q9WU31
Target
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