Sclerostin Protein (SOST) (AA 69-258) (His tag)
Quick Overview for Sclerostin Protein (SOST) (AA 69-258) (His tag) (ABIN7275635)
Target
See all Sclerostin (SOST) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 69-258
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Purification tag / Conjugate
- This Sclerostin protein is labelled with His tag.
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Purpose
- Cynomolgus SOST/Sclerostin Protein
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Sequence
- Gln69-Tyr258
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Characteristics
- Recombinant Cynomolgus SOST/Sclerostin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln69-Tyr258.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Cynomolgus SOST, His Tag at 0.2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-SOST Antibody, hFc Tag with the EC50 of 6.1ng/ml determined by ELISA. See testing image for detail.
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Sclerostin (SOST) (AA 24-213) protein (His-Avi Tag)
SOST Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Sclerostin (SOST) (AA 24-213) protein (His-Avi Tag,Biotin)SOST Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Sclerostin (SOST) (AA 24-211) protein (His tag)SOST Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Sclerostin (SOST) protein (His tag)SOST Origin: Rat Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Sclerostin (SOST) (AA 24-213) protein (His tag,Biotin)SOST Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- Sclerostin (SOST)
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Alternative Name
- SOST
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Background
- SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
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Molecular Weight
- 22.58 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
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NCBI Accession
- XP_005584428
Target
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