TYRO3 Protein (AA 31-419) (His tag)
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- Target See all TYRO3 Proteins
- TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 31-419
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TYRO3 protein is labelled with His tag.
- Purpose
- Mouse TYRO3 Protein
- Sequence
- Arg31-Asp419
- Characteristics
- Recombinant Mouse TYRO3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg31-Asp419.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product TYRO3 Protein
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TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 41-429) protein (His tag)
TYRO3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 41-427) protein (His tag)TYRO3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
TYRO3 Protein Tyrosine Kinase (TYRO3) protein (mFc Tag)TYRO3 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
TYRO3 Protein Tyrosine Kinase (TYRO3) protein (Fc Tag)TYRO3 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 41-428) protein (His tag)TYRO3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 50-150) protein (GST tag)TYRO3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
- Alternative Name
- TYRO3 (TYRO3 Products)
- Background
- The TAM receptors (Tyro3, Axl and MerTK) are promising therapeutic targets on tumor-associated macrophages. The TAM receptors are a family of receptor tyrosine kinases with shared ligands Gas6 and Protein S that skew macrophage polarization towards a pro-tumor M2-like phenotype.In macrophages, the TAM receptors also promote apoptotic cell clearance, a tumor-promoting process called efferocytosis. The TAM receptors bind the "eat-me" signal phosphatidylserine on apoptotic cell membranes using Gas6 and Protein S as bridging ligands.
- Molecular Weight
- 43 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Tris-Bis PAGE result.
- Pathways
- RTK Signaling
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