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TYRO3 Products

(TYRO3 Protein Tyrosine Kinase (TYRO3))

Categories

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010].

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Featured TYRO3 Categories

TYRO3 Antibodies

High quality antibodies with extensive validation data.

TYRO3 ELISA Kits

Reliable ELISA kits for a wide range of species.

TYRO3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TYRO3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IHC (p), IP
Validations
  • (15)
Cat. No. ABIN1501607
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p), IP
Validations
  • (10)
Cat. No. ABIN1501608
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IHC (p), IP
Validations
  • (12)
Cat. No. ABIN1501605
Quantity 100 μL
Datasheet Datasheet

Recommended TYRO3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973922
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN5510662
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN5510661
Quantity 96 tests
Datasheet Datasheet

Recommended TYRO3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275813
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275814
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275812
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TYRO3 products

Kasikara, Davra, Calianese, Geng, Spires, Quigley, Wichroski, Sriram, Suarez-Lopez, Yaffe, Kotenko, De Lorenzo, Birge: "Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer." in: Cancer research, Vol. 79, Issue 10, pp. 2669-2683, (2019) (PubMed).

Santamaria-Barria, Zeng, Greer, Beckman, Seifert, Cohen, Zhang, Crawley, Green, Loo, Maltbaek, DeMatteo: "Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells." in: PLoS ONE, Vol. 14, Issue 5, pp. e0216275, (2019) (PubMed).

Carestia, Mena, Olexen, Ortiz Wilczyñski, Negrotto, Errasti, Gómez, Jenne, Carrera Silva, Schattner: "Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice." in: Cell reports, Vol. 28, Issue 4, pp. 896-908.e5, (2019) (PubMed).

Kasikara, Kumar, Kimani, Tsou, Geng, Davra, Sriram, Devoe, Nguyen, Antes, Krantz, Rymarczyk, Wilczynski, Empig, Freimark, Gray, Schlunegger, Hutchins, Kotenko, Birge: "Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression." in: Molecular cancer research : MCR, Vol. 15, Issue 6, pp. 753-764, (2018) (PubMed).

Chua, Ngo, Situ, Ramirez, Nakano, Morizono: "Protein S and Gas6 induce efferocytosis of HIV-1-infected cells." in: Virology, Vol. 515, pp. 176-190, (2018) (PubMed).

Chan, Carrera Silva, De Kouchkovsky, Joannas, Hao, Hu, Huntsman, Eng, Licona-Limón, Weinstein, Herbert, Craft, Flavell, Repetto, Correale, Burchard, Torgerson, Ghosh, Rothlin: "The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity." in: Science (New York, N.Y.), Vol. 352, Issue 6281, pp. 99-103, (2016) (PubMed).

Yumoto, Eber, Wang, Cackowski, Decker, Lee, Nobre, Aguirre-Ghiso, Jung, Taichman: "Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow." in: Scientific reports, Vol. 6, pp. 36520, (2016) (PubMed).

Kimani, Kumar, Davra, Chang, Kasikara, Geng, Tsou, Wang, Hoque, Boháč, Lewis-Antes, De Lorenzo, Kotenko, Birge: "Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase." in: Cell communication and signaling : CCS, Vol. 14, Issue 1, pp. 19, (2016) (PubMed).

Lyons, Achorn, Kedersha, Anderson, Ivanov: "YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression." in: Nucleic acids research, Vol. 44, Issue 14, pp. 6949-60, (2016) (PubMed).

Zheng, Hedl, Abraham: "TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 4, pp. 1928-37, (2015) (PubMed).

Synonyms and alternative names related to TYRO3

TYRO3 protein tyrosine kinase (TYRO3), TYRO3 protein tyrosine kinase (tyro3), TYRO3 protein tyrosine kinase (Tyro3), TYRO3 protein tyrosine kinase L homeolog (tyro3.L), TYRO3 protein tyrosine kinase 3 (Tyro3), AI323366, brt, Brt, byk, BYK, DKFZp469I0432, dtk, Dtk, Etk-2, ksy, LOC100231598, MGC145734, REK, rse, RSE, Rse, sky, Sky, tif, Tif, TYRO3, Xksy, xksy

Protein level used designations for TYRO3

  • TYRO3 protein tyrosine kinase
  • Tyrosine-protein kinase receptor TYRO3
  • tyrosine-protein kinase receptor TYRO3
  • developmental receptor tyrosine kinase
  • tyrosine-protein kinase DTK
  • tyrosine-protein kinase receptor TYRO3-like
  • tyrosine-protein kinase RSE
  • tyrosine-protein kinase SKY
  • tyrosine-protein kinase TIF
  • tyrosine-protein kinase byk
  • Bruton agammaglobulinemia tyrosine kinase
  • TYRO3 protein tyrosine kinase 3
  • Axl-related receptor tyrosine kinase
  • protein-tyrosine kinase
  • retina-expressed kinase
  • Xenopus kinase of Sky family
  • tyrosine kinase
  • TK19-2
  • etk2/tyro3
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