CD4 Protein (CD4) (Biotin,His-Avi Tag)
Quick Overview for CD4 Protein (CD4) (Biotin,His-Avi Tag) (ABIN7316799)
Target
See all CD4 ProteinsProtein Type
Origin
Source
Purity
Grade
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Purification tag / Conjugate
- This CD4 protein is labelled with Biotin,His-Avi Tag.
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Purpose
- Biotinylated Rhesus macaque CD4 Protein, His,Avitag™ (MALS verified)
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Sequence
- Lys 26 - Trp 390
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Characteristics
- Biotinylated Rhesus macaque CD4,His,Avitag is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Trp 390 (Accession # G7N5T8-1).
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Endotoxin Level
- 1.0 EU per μg
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Comment
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This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 44.0 kDa. The protein migrates as 52-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- CD4
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Alternative Name
- CD4
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Background
- Synonyms:CD4,CD4mut,LEU3,Description:T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
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Molecular Weight
- 44.0 kDa
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Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Target
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