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CD4 Protein (CD4) (Biotin,His-Avi Tag)

Recombinant CD4 protein expressed in HEK-293 Cells.
Catalog No. ABIN7316799

Quick Overview for CD4 Protein (CD4) (Biotin,His-Avi Tag) (ABIN7316799)

Target

See all CD4 Proteins
CD4

Protein Type

Recombinant

Origin

  • 35
  • 8
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Rhesus Monkey

Source

  • 27
  • 9
  • 8
  • 3
  • 2
  • 2
  • 1
  • 1
HEK-293 Cells

Purity

95,00 %

Grade

MALS verified
  • Purification tag / Conjugate

    This CD4 protein is labelled with Biotin,His-Avi Tag.

    Purpose

    Biotinylated Rhesus macaque CD4 Protein, His,Avitag™ (MALS verified)

    Sequence

    Lys 26 - Trp 390

    Characteristics

    Biotinylated Rhesus macaque CD4,His,Avitag is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Trp 390 (Accession # G7N5T8-1).

    Endotoxin Level

    1.0 EU per μg
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  • Comment

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 44.0 kDa. The protein migrates as 52-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C

    Storage Comment

    -20°C
  • Target

    CD4

    Alternative Name

    CD4

    Background

    Synonyms:CD4,CD4mut,LEU3,Description:T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

    Molecular Weight

    44.0 kDa

    Pathways

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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