IL-24 Protein (His tag)
Quick Overview for IL-24 Protein (His tag) (ABIN7448047)
Target
See all IL-24 (IL24) ProteinsProtein Type
Origin
Source
Purity
Grade
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Purification tag / Conjugate
- This IL-24 protein is labelled with His tag.
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Purpose
- Human IL-24 Protein, His Tag (BLI verified)
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Sequence
- Gln 52 - Leu 206
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Characteristics
- Human IL-24 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Gln 52 - Leu 206 (Accession # Q13007-1).
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Endotoxin Level
- 1.0 EU per μg
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Interleukin 24 (IL24) (AA 51-206) (Active) protein (His tag)
IL24 Origin: Human Host: Escherichia coli (E. coli) > 90 % AcA, CC Active
Interleukin 24 (IL24) (AA 58-167) protein (GST tag)IL24 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 1-206) protein (GST tag)IL24 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 1-207) protein (GST tag)IL24 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Comment
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.0 kDa. The protein migrates as 30-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- IL-24 (IL24) (Interleukin 24 (IL24))
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Alternative Name
- IL-24
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Background
- Synonyms:Interleukin-24,IL-24,Melanoma differentiation-associated gene 7 protein,MDA-7,Suppression of tumorigenicity 16 protein,IL24,MDA7,ST16,Description:Interleukin-24 (IL-24, also known as melanoma differentiation-associated gene-7) belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26. Interleukin 24 signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. Upon binding to its receptors, IL-24 induces rapid activation of Stat-1 and Stat-3 transcription factors, which appear to play a role in cell survival and proliferation . Structurally and functionally, IL-24 is highly conserved across species.IL-24 has been shown to possess cancer-specific apoptosis-inducing activity, and has therefore been suggested as a potential anti-cancer agent.
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Molecular Weight
- 20.0 kDa
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
Target
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