ITGA2 Protein (AA 30-1132) (His tag)

Catalog No. ABIN7490739

Recombinant ITGA2 protein expressed in HEK-293 Cells.

Quick Overview for ITGA2 Protein (AA 30-1132) (His tag) (ABIN7490739)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 30-1132

Purification tag / Conjugate: This ITGA2 protein is labelled with His tag.

Purpose: Recombinant human ITGA2 Protein with C-terminal 6xHis tag

Specificity: ITGA2 (Thr30-Thr1132) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: ITGA2

Background: This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Molecular Weight: predicted molecular mass of 121.8 kDa after removal of the signal peptide. The apparent molecular mass of ITGA2-His is 130-250 kDa due to glycosylation.

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex