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CXCR3 Protein (AA 1-53) (mFc Tag)

This Recombinant CXCR3 protein is expressed in HEK-293 Cells.
Catalog No. ABIN7491147

Quick Overview for CXCR3 Protein (AA 1-53) (mFc Tag) (ABIN7491147)

Target

See all CXCR3 Proteins
CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Protein Type

Recombinant

Origin

  • 12
  • 4
  • 2
Human

Source

  • 6
  • 5
  • 4
  • 2
HEK-293 Cells

Purity

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Protein Characteristics

    AA 1-53

    Purification tag / Conjugate

    This CXCR3 protein is labelled with mFc Tag.

    Purpose

    Recombinant human CXCR3 protein with C-terminal mouse Fc tag

    Specificity

    CXCR3 (Met1-Arg53) mFc (Pro99-Lys330)

    Characteristics

    Extracellular Domain Protein

    Purification

    Purified from cell culture supernatant by affinity chromatography
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    Product
    Expression System
    Conjugate
    Origin
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $16,231.82
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

    Alternative Name

    CXCR3

    Background

    This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]

    Molecular Weight

    predicted molecular mass of 32.1 kDa after removal of the signal peptide. The apparent molecular mass of CXCR3-mFc is 25-55 kDa due to glycosylation.

    UniProt

    P49682
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