Quick Overview for CCL23 Protein (ABIN7455691)
Target
See all CCL23 ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human C-C Motif Chemokine 23 is produced by our E.coli expression system and the target gene encoding Arg46-Asn120 is expressed.
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Characteristics
- Extracellular Domain Protein
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Purification
- Affinity purification
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Chemokine (C-C Motif) Ligand 23 (CCL23) (Active) protein
CCL23 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-C Motif) Ligand 23 (CCL23) (AA 22-120) protein (His-IF2DI Tag)CCL23 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-C Motif) Ligand 23 (CCL23) (AA 1-137) protein (GST tag)CCL23 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 23 (CCL23) protein (Myc-DYKDDDDK Tag)CCL23 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))
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Alternative Name
- CCL23
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Background
- Human Chemokine (C-C Motif) Ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family. CCL23 is also known as myeloid progenitor inhibitory factor MPIF-1, CK8 and SCYA23. CCL23 cDNA encodes a 120 amino acid residue precursor protein with a putative 21 amino acid residue signal peptide that is cleaved to generate a 99 amino acid residue mature CCL23 (amino acids 22 -120). Additional N-terminal Processing of the 99 amino acid residue variant can generate a 75 amino acid residue peptide (amino acid 46-120) that is significantly more active than the 99 amino acid residue variant. CCL23 binds to CCR1 with high affinity and has chemotactic activity for monocytes, dendritic cells, and osteoclast precursors. CCL23 enhances angiogenesis of endothelial cells, but reduces the proliferation of progenitor cells giving rise to granulocyte and monocyte lineages.
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Molecular Weight
- 8.7 KDa
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UniProt
- P55773
Target
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