Claudin 3 Protein (CLDN3) (AA 144-156) (Fc Tag)
Quick Overview for Claudin 3 Protein (CLDN3) (AA 144-156) (Fc Tag) (ABIN7491281)
Target
See all Claudin 3 (CLDN3) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 144-156
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Purification tag / Conjugate
- This Claudin 3 protein is labelled with Fc Tag.
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Purpose
- Recombinant Human CLDN3(144-156) Protein with C-terminal human Fc tag
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Specificity
- CLDN3 (Arg144-Lys156) hFc (Glu99-Ala330)
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- Claudin 3 (CLDN3)
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Alternative Name
- CLDN3
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Background
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]
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Molecular Weight
- predicted molecular mass of 27.7 kDa after removal of the signal peptide. The apparent molecular mass of CLDN3(144-156)-hFc is 25-35 kDa due to glycosylation.
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UniProt
- O15551
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Pathways
- Hepatitis C
Target
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