Quick Overview for CCR4 Protein-VLP (ABIN7491560)
Target
See all CCR4 ProteinsProtein Type
Origin
Source
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Purpose
- Human CCR4 full length protein-VLP
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Characteristics
- VLP
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Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 1-360) protein (His tag)
custom-made CCR4 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 1-360) protein (His tag)custom-made CCR4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 1-39) protein (Fc Tag)CCR4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 1-39) protein (mFc Tag)CCR4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Receptor 4 (CCR4) proteinCCR4 Origin: Human Host: Mammalian Cells MNP Membrane Nanoparticle
Chemokine (C-C Motif) Receptor 4 (CCR4) proteinCCR4 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
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Comment
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Virus-like particles (VLPs) are self-assembling multi-protein nanoparticles with similar structural organization and conformation as viruses but without viral genome. The size of the VLP is about 100-150nm. It is secreted from the surface of the cells that express target membrane proteins (MPs). The purified VLPs have the target MPs inserted in a complete bilayer phospholipid membrane structure, mimic the natural membrane-penetrating state of the protein.
VLPs can be used for routine biochemical analysis, including ELISA, SPR affinity analysis, phage display screenings, protein labeling and cell binding experiments, Flow virometry analysis, etc. It can also be used as functional protein antigens to develop active antibodies with high drug potentials because the target protein on VLP exhibits a state like its native state on the cell surface. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
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Alternative Name
- CCR4
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Background
- The protein belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
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Molecular Weight
- The human full length CCR4 Protein has a MW of 41.4 kDa
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UniProt
- P51679
Target
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