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Claudin 6 Protein-VLP (CLDN6) (GFP tag)

CLDN6 Origin: Human Host: HEK-293 Cells VLP

Catalog No. ABIN7489069

Datasheet as PDF

Target See all Claudin 6 (CLDN6) Proteins

Claudin 6 (CLDN6)

Protein Type

VLP
Origin
16

3

1
Human
Source
12

2

2

2

1

1
HEK-293 Cells

Purification tag / Conjugate

This Claudin 6 protein is labelled with GFP tag.

Purpose

Fluorescent Human Claudin-6 / CLDN6 Full Length Protein (VLP)

Sequence

Met 1 - Val 220

Characteristics

Fluorescent Human Claudin-6 Full Length Protein (VLP) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Val 220 (Accession # P56747).

Endotoxin Level

1.0 EU per μg

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Claudin 6 (CLDN6) (AA 138-160) protein (mFc Tag)
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CLDN6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

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Comment

This protein carries a GFP tag. (GFP Fusion,GFP )

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS, Arginine, pH 7.4

Storage

-80 °C

Storage Comment

-70°C, avoid light
Target

Claudin 6 (CLDN6)

Alternative Name

Claudin-6 (CLDN6 Products)

Background

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. Claudin-6, also knows as CLDN6, is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. And it is one of the entry cofactors for hepatitis C virus. The methylation of CLDN6 may be involved in esophageal tumorigenesis. The gene of CLDN6 is adjacent to another family member CLDN9 on chromosome 16.

Pathways

Hepatitis C