LRP1 Protein (Fc Tag)

Catalog No. ABIN7482511

Recombinant LRP1 protein expressed in HEK-293 Cells.

Quick Overview for LRP1 Protein (Fc Tag) (ABIN7482511)

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: 95 %

Grade: MALS verified

Product Details

Purification tag / Conjugate: This LRP1 protein is labelled with Fc Tag.

Purpose: Human LRP-1 / cluster II Protein, Fc Tag (MALS verified)

Sequence: Arg 786 - Leu 1165

Characteristics: Human cluster II Protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Arg 786 - Leu 1165 (Accession # Q07954-1).

Endotoxin Level: 0.1 EU per μg

Application Details

Comment:

This protein carries a human IgG1 Fc tag at the C-terminus. (Fc) The protein has a calculated MW of 68.0kDa. The protein migrates as 75-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Alternative Name: LRP-1

Background: Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is a protein forming a receptor found in the plasma membrane of cells. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor. LRP1 is also a key signalling protein and, thus, involved in various biological processes, such as lipoprotein metabolism and cell motility, and diseases, such as neurodegenerative diseases, atherosclerosis, and cancer.

Molecular Weight: 68.0kDa

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling