NKG2A & CD94 protein (His tag)
Quick Overview for NKG2A & CD94 protein (His tag) (ABIN7482528)
Target
Protein Type
Origin
Source
Purity
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Purification tag / Conjugate
- His tag
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Purpose
- Human NKG2A&CD94 Protein, His Tag
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Sequence
- Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94)
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Characteristics
- Human NKG2A&CD94 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94) (Accession # P26715-1 (NKG2A) & Q13241-1 (CD94).
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Endotoxin Level
- 1.0 EU per μg
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NKG2A & CD94 (AA 100-233) protein (mFc Tag)
Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
NKG2A & CD94 (AA 100-233) protein (His-Avi Tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
NKG2A & CD94 (AA 100-233) protein (Fc Tag,DYKDDDDK Tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
NKG2A & CD94 (AA 100-233) protein (His-Avi Tag,Biotin)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
NKG2A & CD94 (AA 100-219) protein (Fc Tag,DYKDDDDK Tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
NKG2A & CD94 (AA 94-233) protein (His tag,DYKDDDDK Tag)Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
NKG2A & CD94 (AA 98-244) protein (mFc Tag)Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
NKG2A & CD94 (AA 113-233) protein (Fc Tag)Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
NKG2A & CD94 (AA 113-233), (AA 57-179) (Active) protein (Fc Tag,AVI tag,Biotin)Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Comment
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This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 30.7 kDa. The protein migrates as 37-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- NKG2A & CD94
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Alternative Name
- NKG2A&CD94
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Background
- CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
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Molecular Weight
- 30.7 kDa
Target
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