tau-441 (P301L) protein (His tag)

Catalog No. ABIN7482544

Recombinant protein expressed in Escherichia coli (E. coli).

Quick Overview for tau-441 (P301L) protein (His tag) (ABIN7482544)

Target: tau-441

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: 90 %

Product Details

Protein Characteristics: P301L

Purification tag / Conjugate: His tag

Purpose: Human Tau-441 / 2N4R (P301L) Protein, His Tag

Sequence: Met 1 - Leu 441

Characteristics: Human Tau-441 (P301L), His Tag is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8 (P301L).

Endotoxin Level: 1.0 EU per μg

Application Details

Comment:

This protein carries a polyhistidine tag at the N-terminus. (10xHis) The protein has a calculated MW of 47.8 kDa. The protein migrates as 38-66 kDa under reducing (R) condition (SDS-PAGE).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: tau-441

Background: Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Molecular Weight: 47.8 kDa