tau-441 (Active) Protein
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
95 %
Active
-
- Target
- tau-441
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purpose
- Human Tau-441 / 2N4R Pre-formed Fibrils Protein, Tag Free (ThT active)
- Sequence
- Met 1 - Leu 441
- Characteristics
- Human Tau-441 Pre-formed Fibrils, Tag Free is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8).
- Purity
- 95 %
- Endotoxin Level
- 0.05 EU per μg
-
tau-441 (AA 1-441) protein (His tag)
Origin: Human Host: Escherichia coli (E. coli) Recombinant >90 % as determined by reduced SDS-PAGE.
-
- Comment
-
This protein carries no "tag". () The protein has a calculated MW of 45.8 kDa.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- 50 mM Tris, 150 mM NaCl, 1 mM DTT, 1 mM EDTA, pH 7.5
- Storage
- -80 °C
- Storage Comment
- -70°C
-
- Target
- tau-441
- Background
- Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.
- Molecular Weight
- 45.8 kDa
- NCBI Accession
- NP_005901
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