TNFSF15 Protein
Quick Overview for TNFSF15 Protein (ABIN7488820)
Target
See all TNFSF15 ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Human TL1A / TNFSF15 Protein, His Tag
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Sequence
- Met 1 - Leu 192
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Characteristics
- Human TL1A Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Leu 192 (Accession # O95150-2).
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Endotoxin Level
- 1.0 EU per μg
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Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 91-251), (Trimer) protein (His-DYKDDDDK Tag)
TNFSF15 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE, > 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 61-252) protein (His-Avi Tag,Biotin)TNFSF15 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 1-251) protein (His tag)custom-made TNFSF15 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 1-252) protein (His tag)custom-made TNFSF15 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 61-252) protein (His-Avi Tag)TNFSF15 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 61-252) protein (Fc Tag)TNFSF15 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-251) protein (His-DYKDDDDK-Strep II Tag)TNFSF15 Origin: Human Host: HEK-293T Cells Recombinant ELISA, SDS, WB, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-251) protein (His tag)TNFSF15 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 1-251) protein (GST tag)TNFSF15 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-251) (Active) protein (His tag)TNFSF15 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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Comment
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This protein carries a polyhistidine tag at the N-terminus. () The protein has a calculated MW of 23.7 kDa. The protein migrates as 30 kDa and 31-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
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Alternative Name
- TL1A
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Background
- TNF-like cytokine 1A (TL1A) and its receptors, death receptor 3 (DR3) and decoy receptor 3 (DcR3) are members of the TNF and TNF receptor superfamilies of proteins, respectively. Binding of APC-derived TL1A to lymphocytic DR3 provides co-stimulatory signals for activated lymphocytes. DR3 signaling affects not only the proliferative activity of and cytokine production by effector lymphocytes, but also critically influences the development and suppressive function of regulatory T-cells. Whereas, DcR3 restricts the function of the TL1A/DR3 complex: attenuating T-cell activation and downregulating the secretion of pro-inflammatory cytokines. Together with DR3 and DcR3, TL1A constitutes a cytokine system that actively interferes with the regulation of immune responses.
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Molecular Weight
- 23.7 kDa
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Pathways
- Positive Regulation of Endopeptidase Activity, Autophagy
Target
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