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TPBG Protein (Fc Tag)

This Recombinant TPBG protein is produced in HEK-293 Cells.
Catalog No. ABIN7489088

Quick Overview for TPBG Protein (Fc Tag) (ABIN7489088)

Target

See all TPBG Proteins
TPBG (Trophoblast Glycoprotein (TPBG))

Protein Type

Recombinant

Origin

  • 24
  • 3
  • 2
  • 2
  • 1
Mouse

Source

  • 21
  • 3
  • 2
  • 2
  • 2
  • 1
HEK-293 Cells

Purity

90 %

Grade

MALS verified
  • Purification tag / Conjugate

    This TPBG protein is labelled with Fc Tag.

    Purpose

    Mouse TPBG / 5T4 Protein, Fc Tag (MALS verified)

    Sequence

    Ser 32 - Ser 361

    Characteristics

    Mouse TPBG Protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Ser 32 - Ser 361 (Accession # Q9Z0L0-1).

    Endotoxin Level

    1.0 EU per μg
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  • Comment

    This protein carries a human IgG1 Fc tag at the C-terminus. (Fc) The protein has a calculated MW of 62.2 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5

    Storage

    -20 °C

    Storage Comment

    -20°C
  • Target

    TPBG (Trophoblast Glycoprotein (TPBG))

    Alternative Name

    TPBG

    Background

    Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. TPBG is expressed by all types of trophoblasts as early as 9 weeks of development.

    Molecular Weight

    62.2 kDa
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