Rubella Virus E2 protein (His tag)

Catalog No. ABIN7482619

Recombinant protein expressed in HEK-293 Cells.

Quick Overview for Rubella Virus E2 protein (His tag) (ABIN7482619)

Target: Rubella Virus E2

Protein Type: Recombinant

Origin: Rubella Virus (RuV)

Source: HEK-293 Cells

Purity: 90 %

Product Details

Purification tag / Conjugate: His tag

Purpose: Rubella virus Glycoprotein E2 (strain M33) (RUBV), His Tag (HPLC-verified)

Sequence: Gly 301- Ala 532

Characteristics: Rubella virus Glycoprotein E2 (strain M33) (RUBV), His Tag is expressed from human 293 cells (HEK293). It contains AA Gly 301- Ala 532 (Accession # P08563).

Endotoxin Level: 1.0 EU per μg

Application Details

Comment:

This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 26.7 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: Rubella Virus E2

Alternative Name: Rubella virus Glycoprotein E2

Target Type: Viral Protein

Background: Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.

Molecular Weight: 26.7 kDa