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Rubella Virus E2 protein (His tag)

Origin: Rubella Virus (RuV) Host: HEK-293 Cells Recombinant 90 %
Catalog No. ABIN7482619
  • Target
    Rubella Virus E2
    Protein Type
    Recombinant
    Origin
    Rubella Virus (RuV)
    Source
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    His tag
    Purpose
    Rubella virus Glycoprotein E2 (strain M33) (RUBV), His Tag (HPLC-verified)
    Sequence
    Gly 301- Ala 532
    Characteristics
    Rubella virus Glycoprotein E2 (strain M33) (RUBV), His Tag is expressed from human 293 cells (HEK293). It contains AA Gly 301- Ala 532 (Accession # P08563).
    Purity
    90 %
    Endotoxin Level
    1.0 EU per μg
  • Comment

    This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 26.7 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    Rubella Virus E2
    Alternative Name
    Rubella virus Glycoprotein E2
    Target Type
    Viral Protein
    Background
    Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.
    Molecular Weight
    26.7 kDa
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