Rubella Virus E2 protein (His tag)
Origin: Rubella Virus (RuV)
Host: HEK-293 Cells
Recombinant
90 %
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- Target
- Rubella Virus E2
- Protein Type
- Recombinant
- Origin
- Rubella Virus (RuV)
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- His tag
- Purpose
- Rubella virus Glycoprotein E2 (strain M33) (RUBV), His Tag (HPLC-verified)
- Sequence
- Gly 301- Ala 532
- Characteristics
- Rubella virus Glycoprotein E2 (strain M33) (RUBV), His Tag is expressed from human 293 cells (HEK293). It contains AA Gly 301- Ala 532 (Accession # P08563).
- Purity
- 90 %
- Endotoxin Level
- 1.0 EU per μg
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-
- Comment
-
This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 26.7 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- Rubella Virus E2
- Alternative Name
- Rubella virus Glycoprotein E2
- Target Type
- Viral Protein
- Background
- Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.
- Molecular Weight
- 26.7 kDa
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