Osteomodulin Protein (OMD) (AA 21-421) (His tag)
This Recombinant Osteomodulin protein is expressed in HEK-293 Cells.
Catalog No. ABIN7504495
Quick Overview for Osteomodulin Protein (OMD) (AA 21-421) (His tag) (ABIN7504495)
Target
See all Osteomodulin (OMD) Proteins
Osteomodulin (OMD)
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Purity
> 95 % as determined by Tris-Bis PAGE
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Protein Characteristics
- AA 21-421
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Purification tag / Conjugate
- This Osteomodulin protein is labelled with His tag.
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Purpose
- Human Osteomodulin Protein
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Sequence
- Gln21-Glu421
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Characteristics
- Recombinant Human Osteomodulin Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln21-Glu421.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Osteomodulin (OMD) (AA 1-421) protein (GST tag)
OMD Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Osteomodulin (OMD) protein (His tag)OMD Origin: Mouse Host: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- Osteomodulin (OMD)
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Alternative Name
- Osteomodulin
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Background
- Osteomodulin (OMD) is a member of the small leucine-rich repeat proteoglycan family, which is involved in the organization of the extracellular matrix. OMD is located in bone tissue and is reportedly important for bone mineralization. Mechanistically, OMD could bind to BMP2 via its terminal leucine-rich repeats and formed complexes with BMP2 and its membrane receptors, thus promoting BMP/SMAD signal transduction. In addition, OMD was a putative target gene of SMAD4, which plays a pivotal role in this pathway.
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Molecular Weight
- 48.25 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
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UniProt
- Q99983
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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