PKM2 Protein (AA 2-531) (His tag)
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- Target See all PKM2 Proteins
- PKM2 (Pyruvate Kinase M2 (PKM2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-531
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Origin
- Mouse
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This PKM2 protein is labelled with His tag.
- Purpose
- Mouse PKM2 Protein
- Sequence
- Pro2-Pro531
- Characteristics
- Recombinant Mouse PKM2 Protein is expressed from Baculovirus-Insect Cells with His tag at the N-terminus.It contains Pro2-Pro531.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product PKM2 Protein
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Pyruvate Kinase M2 (PKM2) (AA 1-531) protein (GST tag)
PKM2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Pyruvate Kinase M2 (PKM2) (AA 1-531) protein (His tag)PKM2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Pyruvate Kinase M2 (PKM2) (AA 1-531) protein (His tag)PKM2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Pyruvate Kinase M2 (PKM2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PKM2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl ( pH 7.0). Normally 8 % mannitol is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PKM2 (Pyruvate Kinase M2 (PKM2))
- Alternative Name
- PKM2 (PKM2 Products)
- Background
- Pyruvate kinase M2 (PKM2), a key rate-limiting enzyme of glycolysis, is a critical regulator in tumor metabolism. PKM2 has been demonstrated to overexpressed in various cancers and promoted proliferation and metastasis of tumor cells.
- Molecular Weight
- 58.95 kDa same as Tris-Bis PAGE result.
- NCBI Accession
- NP_001240812
- Pathways
- Warburg Effect
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