Tropomyosin Protein (AA 1-284) (His tag)
Quick Overview for Tropomyosin Protein (AA 1-284) (His tag) (ABIN7504554)
Target
See all Tropomyosin (TPM1) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 1-284
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Purification tag / Conjugate
- This Tropomyosin protein is labelled with His tag.
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Purpose
- Human TPM1 Protein
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Sequence
- Met1-Met284
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Characteristics
- Recombinant Human TPM1 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Met284.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Tropomyosin 1 (Alpha) (TPM1) (AA 1-284) protein (His tag)
custom-made TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tropomyosin 1 (Alpha) (TPM1) (AA 1-284) protein (His tag)custom-made TPM1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tropomyosin 1 (Alpha) (TPM1) (AA 1-245) protein (GST tag)TPM1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS, 150 mM NaCl ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
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Alternative Name
- TPM1
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Background
- Tropomyosin-1 (TPM1), a widely expressed actin-binding protein, is downregulated in many tumors and associated with cancer progression. TPM1 overexpression in RCC cell lines can induce tumor cell apoptosis via the p53-mediated mitochondrial pathway. Further studies are needed to fully elucidate the potential of TPM1 as a candidate for RCC targeted therapy in the future.
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Molecular Weight
- 34.26 kDa same as Tris-Bis PAGE result.
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NCBI Accession
- NP_000357
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Pathways
- Regulation of Actin Filament Polymerization
Target
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