Annexin V Protein (AA 1-320) (His tag)

Catalog No. ABIN7504910

This Recombinant Annexin V protein is expressed in Escherichia coli (E. coli).

Quick Overview for Annexin V Protein (AA 1-320) (His tag) (ABIN7504910)

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Protein Type: Recombinant

Origin: Cow

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 1-320

Purification tag / Conjugate: This Annexin V protein is labelled with His tag.

Sequence: Met 1-Asp 320

Characteristics: A DNA sequence encoding the Bovine Annexin V protein (P81287) (Met 1-Asp 320) was expressed with N-His tag.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Alternative Name: Annexin V

Background:

Abbreviation: Annexin V

Target Synonym: ANXA5,Annexin V,Unconjugated Annexin V,Annexin-5,Anchorin CII,Calphobindin I,Endonexin II,Lipocortin V,Placental anticoagulant protein 4,Thromboplastin inhibitor,Vascular anticoagulant-alpha

Background: Peptidyl-prolyl cis-trans isomerase A, also known as PPIase A, Rotamase A, Cyclophilin A, Cyclosporin A-binding protein, PPIA and CYPA, is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. PPIA / Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA / Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli, and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. PPIA / Cyclophilin A can interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.

Molecular Weight:

Calculated MW: 35.09 kDa

Observed MW: 35 kDa

UniProt: P81287

Pathways: Apoptosis