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CD59 Protein (CD59) (AA 26-102) (His tag)

This Recombinant CD59 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7504948

Quick Overview for CD59 Protein (CD59) (AA 26-102) (His tag) (ABIN7504948)

Target

See all CD59 Proteins
CD59

Protein Type

Recombinant

Origin

  • 15
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Human

Source

  • 15
  • 11
  • 6
  • 2
  • 1
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Escherichia coli (E. coli)

Application

Immunogen (Imm)

Purity

> 90 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 26-102

    Purification tag / Conjugate

    This CD59 protein is labelled with His tag.

    Sequence

    Leu26-Asn102

    Characteristics

    A DNA sequence encoding the Human CD59 glycoprotein protein (P13987-1) (26L-102N) was expressed with a polyhistidine tag at the N/C-terminus.
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    CD59

    Alternative Name

    CD59 glyco

    Background

    Abbreviation: CD59

    Target Synonym: 16.3A5,1F5,1F5,EJ16,EJ30,EL32,FLJ38134,FLJ92039,G344,HRF 20,Ly 6

    Background: Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

    Molecular Weight

    Calculated MW: 10.2 kDa

    Observed MW: 14-16 kDa

    UniProt

    P13987-1

    Pathways

    Complement System
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