IL-6 Receptor Protein (AA 20-365) (His tag)
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- Target See all IL-6 Receptor (IL6R) Proteins
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-365
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IL-6 Receptor protein is labelled with His tag.
- Application
- Immunogen (Imm)
- Sequence
- Leu20-Pro365
- Characteristics
- A DNA sequence encoding the Human IL6R protein (P08887) (20L-365L) was expressed with a polyhistidine tag at the N-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IL6R Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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used as Immunogen for (ABIN6999915, ABIN7234277, ABIN7234278 and ABIN7234279)
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- Alternative Name
- IL6R (IL6R Products)
- Background
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Abbreviation: IL6R
Target Synonym: IL-6RA,CD 126,CD126,CD126 antigen,gp80,IL 6R 1,IL 6R alpha,IL 6R,IL-6 receptor alpha chain,IL-6 receptor subunit alpha,IL-6R 1,IL-6R subunit alpha,IL-6R-alpha,IL-6RA,IL6Q,Il6r,IL6RA,IL6RA,IL6RQ,Interleukin 6 receptor,interleukin 6 receptor,alpha,Interleukin-6 receptor subunit alpha,Membrane glycoprotein 80,MGC30256
Background: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
- Molecular Weight
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Calculated MW: 39.9 kDa
Observed MW: 38-40 kDa
- UniProt
- P08887
- Pathways
- JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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