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Ataxin 2 Protein (ATXN2) (AA 460-600) (GST tag)

This Recombinant Ataxin 2 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7505038

Quick Overview for Ataxin 2 Protein (ATXN2) (AA 460-600) (GST tag) (ABIN7505038)

Target

See all Ataxin 2 (ATXN2) Proteins
Ataxin 2 (ATXN2)

Protein Type

Recombinant

Origin

  • 5
  • 1
Human

Source

  • 2
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 460-600

    Purification tag / Conjugate

    This Ataxin 2 protein is labelled with GST tag.

    Sequence

    Leu 460-Ser 600

    Characteristics

    A DNA sequence encoding the Human ATXN2 protein (Q99700) (Leu460-Ser600) was expressed with a N-GST tag.
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    Conjugate His tag
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    Ataxin 2 (ATXN2)

    Alternative Name

    ATXN2

    Background

    Abbreviation: ATXN2

    Target Synonym: Ataxin-2,Spinocerebellar ataxia type 2 protein,Trinucleotide repeat-containing gene 13 protein,ATXN2,ATX2,SCA2,TNRC13

    Background: Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.

    Molecular Weight

    Calculated MW: 40.4 kDa

    Observed MW: 42 kDa

    UniProt

    Q99700

    Pathways

    Ribonucleoprotein Complex Subunit Organization
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