Ataxin 2 Protein (ATXN2) (AA 460-600) (GST tag)
Quick Overview for Ataxin 2 Protein (ATXN2) (AA 460-600) (GST tag) (ABIN7505038)
Target
See all Ataxin 2 (ATXN2) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 460-600
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Purification tag / Conjugate
- This Ataxin 2 protein is labelled with GST tag.
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Sequence
- Leu 460-Ser 600
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Characteristics
- A DNA sequence encoding the Human ATXN2 protein (Q99700) (Leu460-Ser600) was expressed with a N-GST tag.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- Ataxin 2 (ATXN2)
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Alternative Name
- ATXN2
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Background
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Abbreviation: ATXN2
Target Synonym: Ataxin-2,Spinocerebellar ataxia type 2 protein,Trinucleotide repeat-containing gene 13 protein,ATXN2,ATX2,SCA2,TNRC13
Background: Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.
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Molecular Weight
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Calculated MW: 40.4 kDa
Observed MW: 42 kDa
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UniProt
- Q99700
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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