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Lactate Dehydrogenase A Protein (LDHA) (AA 2-332) (His tag)

This Recombinant Lactate Dehydrogenase A protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7505053

Quick Overview for Lactate Dehydrogenase A Protein (LDHA) (AA 2-332) (His tag) (ABIN7505053)

Target

See all Lactate Dehydrogenase A (LDHA) Proteins
Lactate Dehydrogenase A (LDHA)

Protein Type

Recombinant

Origin

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Human

Source

  • 22
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Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 2-332

    Purification tag / Conjugate

    This Lactate Dehydrogenase A protein is labelled with His tag.

    Sequence

    Ala 2-Phe 332

    Characteristics

    A DNA sequence encoding the Human LDHA protein (P00338) (Ala 2-Phe 332) was expressed with a N-His tag.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    Lactate Dehydrogenase A (LDHA)

    Alternative Name

    LDHA

    Background

    Abbreviation: LDHA

    Target Synonym: L-Lactate Dehydrogenase A Chain,LDH-A,Cell Proliferation-Inducing Gene 19 Protein,LDH Muscle Subunit,LDH-M,Renal Carcinoma Antigen NY-REN-59,LDHA

    Background: L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.

    Molecular Weight

    Calculated MW: 36.3 kDa

    Observed MW: 39 kDa

    UniProt

    P00338

    Pathways

    Warburg Effect
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