BMP2 Protein (AA 283-396) (His tag)
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- Target See all BMP2 Proteins
- BMP2 (Bone Morphogenetic Protein 2 (BMP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 283-396
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BMP2 protein is labelled with His tag.
- Sequence
- Gln 283-Arg 396
- Characteristics
- A DNA sequence encoding the Human BMP2 protein (P12643) (Gln 283-Arg 396) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- BMP2 (Bone Morphogenetic Protein 2 (BMP2))
- Alternative Name
- BMP2 (BMP2 Products)
- Background
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Abbreviation: BMP2
Target Synonym: BDA2,BDA2A,BMP-2,BMP2A,BMP2
Background: BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.
- Molecular Weight
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Calculated MW: 12.43 kDa
Observed MW: 12 kDa
- UniProt
- P12643
- Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
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