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CCL5 Protein (AA 25-91) (GST-His-Tag)

Recombinant CCL5 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7505127

Quick Overview for CCL5 Protein (AA 25-91) (GST-His-Tag) (ABIN7505127)

Target

See all CCL5 Proteins
CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Protein Type

Recombinant

Origin

  • 20
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Source

  • 31
  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 25-91

    Purification tag / Conjugate

    This CCL5 protein is labelled with GST-His-Tag.

    Sequence

    Pro 25-Ser 91

    Characteristics

    A DNA sequence encoding the Human RANTES protein (P13501) (Pro 25-Ser 91) was expressed with a N-GST&C-His tag.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

    Alternative Name

    RANTES

    Background

    Abbreviation: RANTES

    Target Synonym: C-C Motif Chemokine 5,EoCP,Eosinophil Chemotactic Cytokine,SIS-Delta,Small-Inducible Cytokine A5,T Cell-Specific Protein P228,TCP228,T-Cell-Specific Protein RANTES,CCL5,D17S136E,SCYA5

    Background: Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.

    Molecular Weight

    Calculated MW: 32.26 kDa

    Observed MW: 42 kDa

    UniProt

    P13501

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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