CCL5 Protein (AA 25-91) (GST-His-Tag)
Quick Overview for CCL5 Protein (AA 25-91) (GST-His-Tag) (ABIN7505127)
Target
See all CCL5 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 25-91
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Purification tag / Conjugate
- This CCL5 protein is labelled with GST-His-Tag.
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Sequence
- Pro 25-Ser 91
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Characteristics
- A DNA sequence encoding the Human RANTES protein (P13501) (Pro 25-Ser 91) was expressed with a N-GST&C-His tag.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
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Alternative Name
- RANTES
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Background
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Abbreviation: RANTES
Target Synonym: C-C Motif Chemokine 5,EoCP,Eosinophil Chemotactic Cytokine,SIS-Delta,Small-Inducible Cytokine A5,T Cell-Specific Protein P228,TCP228,T-Cell-Specific Protein RANTES,CCL5,D17S136E,SCYA5
Background: Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.
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Molecular Weight
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Calculated MW: 32.26 kDa
Observed MW: 42 kDa
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UniProt
- P13501
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
Target
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