Calnexin Protein (CANX) (AA 21-300) (His tag)
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- Target See all Calnexin (CANX) Proteins
- Calnexin (CANX)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-300
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Calnexin protein is labelled with His tag.
- Sequence
- His 21-Lys 300
- Characteristics
- A DNA sequence encoding the CANX/Calnexin protein (P27824) (His 21-Lys 300) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CANX Protein
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Calnexin (CANX) (AA 21-481) protein
CANX Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Calnexin (CANX) (Transcript Variant 2) protein (His tag)CANX Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Calnexin (CANX) proteinCANX Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Calnexin (CANX) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CANX Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Calnexin (CANX)
- Alternative Name
- CANX (CANX Products)
- Background
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Abbreviation: CANX,Calnexin
Target Synonym: Calnexin,IP90,Major Histocompatibility Complex Class I Antigen-Binding Protein p88,p90,CANX
Background: Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.
- Molecular Weight
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Calculated MW: 30.69 kDa
Observed MW: 42 kDa
- UniProt
- P27824
- Pathways
- MAPK Signaling, Thyroid Hormone Synthesis
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